QCast: Data-Driven Dialogue in Drug Development

Episode 21: The Role of Reconciliation in Clinical Data Management

Quanticate Episode 21

In this QCast episode, Jullia and Tom unpack data reconciliation in clinical data management — what it is, why it underpins data integrity and safety oversight, and how to plan, run, and document it so analyses reflect the truth across clinical, safety, and vendor systems. 

Key Takeaways

  •  Map streams early, set owners and cadence, lock vendor specifications.
  • Prioritise high-risk data such as safety and endpoints, monitor trends.
  • Standardise units, ranges and identifiers, enforce change control and stable keys.
  • Automate cross-system checks and dashboards, keep audit-ready logs and reconciliation records.


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📝 Episode Notes & Transcript: Find show notes, resources, and a full transcript at quanticate.com/podcast.
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About Quanticate

Founded in 1994, Quanticate is a biometrics-focused CRO with over 30 years' experience delivering expert clinical and post-marketing data services worldwide. Specialising in the collection, management, standardisation, analysis, and reporting of data, we support pharma and biotech companies globally with high-quality solutions for clinical development. We specialise in:

  • Clinical Data Capture & Management
  • Biostatistics & Statistical Consultancy
  • Statistical Programming & PK/PD Analysis
  • Medical Writing & Pharmacovigilance
  • Regulatory & Submission Support
  • AI & Automation
  • Post-Marketing Safety & Real-World Data

Quanticate is committed to delivering expertise and solutions that drive the success of clinical development worldwide.